About   Help   FAQ
Symbol
Name
ID
Icosl
icos ligand
MGI:1354701
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
abnormal class switch recombination
abnormal T cell differentiation
abnormal T-helper 2 cell differentiation
abnormal spleen morphology
small spleen
abnormal spleen germinal center morphology
decreased spleen germinal center number
decreased spleen germinal center size
abnormal immunoglobulin level
decreased IgA level
decreased IgE level
decreased IgG1 level
decreased IgG2a level
decreased IgG2b level
decreased IgG level
decreased IgM level
abnormal T-helper 2 physiology
abnormal interferon level
abnormal immune system physiology
abnormal humoral immune response
abnormal immune serum protein physiology
increased interferon-gamma secretion
abnormal interleukin secretion
decreased interleukin-10 secretion
decreased interleukin-4 secretion
decreased inflammatory response
Availability Mouse Genotype
Icosltm1Cdon/Icosltm1Cdon
Icosltm1Kplm/Icosltm1Kplm
Icosltm1Mak/Icosltm1Mak *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory